Cargando…
In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides
Cancer and other disease states can change the landscape of proteins post-translationally tagged with ubiquitin (Ub) chains. Molecules capable of modulating the functions of Ub chains are potential therapeutic agents, but their discovery represents a significant challenge. Recently, it was shown tha...
Autores principales: | Rogers, Joseph M., Nawatha, Mickal, Lemma, Betsegaw, Vamisetti, Ganga B., Livneh, Ido, Barash, Uri, Vlodavsky, Israel, Ciechanover, Aaron, Fushman, David, Suga, Hiroaki, Brik, Ashraf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232551/ https://www.ncbi.nlm.nih.gov/pubmed/34179781 http://dx.doi.org/10.1039/d0cb00179a |
Ejemplares similares
-
Correction: In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides
por: Rogers, Joseph M., et al.
Publicado: (2021) -
The Development of a Fluorescence‐Based Competitive Assay Enabled the Discovery of Dimeric Cyclic Peptide Modulators of Ubiquitin Chains
por: Vamisetti, Ganga B., et al.
Publicado: (2021) -
Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation
por: Lemma, Betsegaw, et al.
Publicado: (2023) -
Selective macrocyclic peptide modulators of Lys63-linked ubiquitin chains disrupt DNA damage repair
por: Vamisetti, Ganga B., et al.
Publicado: (2022) -
p62 at the crossroad of the ubiquitin-proteasome system and autophagy
por: Cohen-Kaplan, Victoria, et al.
Publicado: (2016)