Breeding and Maintenance of Immunodeficient Mouse Lines under SPF Conditions—A Call for Individualized Severity Analyses and Approval Procedures

SIMPLE SUMMARY: In the EU, the breeding of genetically modified laboratory animals is defined as an animal experiment, if the animals may experience pain, suffering or harm due to the genetic modification. In most cases, modifications of the immune system do not lead to pain, suffering, or harm give...

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Detalles Bibliográficos
Autores principales: Kammertoens, Thomas, Jeuthe, Sarah, Baranzke, Heike, Klippert, Antonina, Thöne-Reineke, Christa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232569/
https://www.ncbi.nlm.nih.gov/pubmed/34203900
http://dx.doi.org/10.3390/ani11061789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232569/
https://www.ncbi.nlm.nih.gov/pubmed/34203900
http://dx.doi.org/10.3390/ani11061789

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