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Breeding and Maintenance of Immunodeficient Mouse Lines under SPF Conditions—A Call for Individualized Severity Analyses and Approval Procedures
SIMPLE SUMMARY: In the EU, the breeding of genetically modified laboratory animals is defined as an animal experiment, if the animals may experience pain, suffering or harm due to the genetic modification. In most cases, modifications of the immune system do not lead to pain, suffering, or harm give...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232569/ https://www.ncbi.nlm.nih.gov/pubmed/34203900 http://dx.doi.org/10.3390/ani11061789 |