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Interactions between Cancer-Associated Fibroblasts and T Cells in the Pancreatic Tumor Microenvironment and the Role of Chemokines
SIMPLE SUMMARY: Despite advances in therapeutic modalities, the five-year overall survival for pancreatic cancer is still less than 10%. Pancreatic tumors are characterized by a highly fibrotic stroma comprised of activated cancer-associated fibroblasts (CAFs) which surrounds the cancer cells. Pancr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232575/ https://www.ncbi.nlm.nih.gov/pubmed/34203869 http://dx.doi.org/10.3390/cancers13122995 |