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Interactions between Cancer-Associated Fibroblasts and T Cells in the Pancreatic Tumor Microenvironment and the Role of Chemokines

SIMPLE SUMMARY: Despite advances in therapeutic modalities, the five-year overall survival for pancreatic cancer is still less than 10%. Pancreatic tumors are characterized by a highly fibrotic stroma comprised of activated cancer-associated fibroblasts (CAFs) which surrounds the cancer cells. Pancr...

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Detalles Bibliográficos
Autores principales: Gorchs, Laia, Kaipe, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232575/
https://www.ncbi.nlm.nih.gov/pubmed/34203869
http://dx.doi.org/10.3390/cancers13122995