The RAD51-FFPE Test; Calibration of a Functional Homologous Recombination Deficiency Test on Diagnostic Endometrial and Ovarian Tumor Blocks

SIMPLE SUMMARY: Rapid and reliable identification of patients with homologous recombination deficient (HRD) tumors is important for treatment choice as these tumors tend to respond well to platinum-based chemotherapy and PARP inhibitors (PARPi). In this study, a RAD51-based functional HRD test that...

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Detalles Bibliográficos
Autores principales: van Wijk, Lise M., Kramer, Claire J. H., Vermeulen, Sylvia, ter Haar, Natalja T., de Jonge, Marthe M., Kroep, Judith R., de Kroon, Cor D., Gaarenstroom, Katja N., Vrieling, Harry, Bosse, Tjalling, Vreeswijk, Maaike P. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232577/
https://www.ncbi.nlm.nih.gov/pubmed/34203855
http://dx.doi.org/10.3390/cancers13122994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232577/
https://www.ncbi.nlm.nih.gov/pubmed/34203855
http://dx.doi.org/10.3390/cancers13122994

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