Studying the Impact of the Temperature and Sorbed Water during Microwave-Induced In Situ Amorphization: A Case Study of Celecoxib and Polyvinylpyrrolidone

Microwave-induced in situ amorphization of a drug into a polymeric amorphous solid dispersion (ASD) has been suggested to follow a dissolution process of the drug into the polymeric network, at temperatures above the glass transition temperature (T(g)) of the polymer. Thus, increasing the compact te...

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Detalles Bibliográficos
Autores principales: Hempel, Nele-Johanna, Knopp, Matthias M., Löbmann, Korbinian, Berthelsen, Ragna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232578/
https://www.ncbi.nlm.nih.gov/pubmed/34203828
http://dx.doi.org/10.3390/pharmaceutics13060886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232578/
https://www.ncbi.nlm.nih.gov/pubmed/34203828
http://dx.doi.org/10.3390/pharmaceutics13060886

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