The Anti-Tumor Effect of Lactococcus lactis Bacteria-Secreting Human Soluble TRAIL Can Be Enhanced by Metformin Both In Vitro and In Vivo in a Mouse Model of Human Colorectal Cancer

SIMPLE SUMMARY: Colorectal cancer (CRC) is a major cause of morbidity and mortality in Europe, and accounts for over 10% of all cancer-related deaths worldwide. These indicate an urgent need for novel therapeutic options in CRC. Here, we analysed if genetically modified non-pathogenic Lactococcus la...

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Detalles Bibliográficos
Autores principales: Kaczmarek, Katarzyna, Więckiewicz, Jerzy, Węglarczyk, Kazimierz, Siedlar, Maciej, Baran, Jarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232584/
https://www.ncbi.nlm.nih.gov/pubmed/34203951
http://dx.doi.org/10.3390/cancers13123004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232584/
https://www.ncbi.nlm.nih.gov/pubmed/34203951
http://dx.doi.org/10.3390/cancers13123004

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