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Antimicrobial Activity of a Library of Thioxanthones and Their Potential as Efflux Pump Inhibitors

The overexpression of efflux pumps is one of the causes of multidrug resistance, which leads to the inefficacy of drugs. This plays a pivotal role in antimicrobial resistance, and the most notable pumps are the AcrAB-TolC system (AcrB belongs to the resistance-nodulation-division family) and the Nor...

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Detalles Bibliográficos
Autores principales: Durães, Fernando, Palmeira, Andreia, Cruz, Bárbara, Freitas-Silva, Joana, Szemerédi, Nikoletta, Gales, Luís, da Costa, Paulo Martins, Remião, Fernando, Silva, Renata, Pinto, Madalena, Spengler, Gabriella, Sousa, Emília
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232621/
https://www.ncbi.nlm.nih.gov/pubmed/34203998
http://dx.doi.org/10.3390/ph14060572