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Critical Role of Hemopexin Mediated Cytoprotection in the Pathophysiology of Sickle Cell Disease

Circulating hemopexin is the primary protein responsible for the clearance of heme; therefore, it is a systemic combatant against deleterious inflammation and oxidative stress induced by the presence of free heme. This role of hemopexin is critical in hemolytic pathophysiology. In this review, we ou...

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Detalles Bibliográficos
Autores principales: Ashouri, Rani, Fangman, Madison, Burris, Alicia, Ezenwa, Miriam O., Wilkie, Diana J., Doré, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232622/
https://www.ncbi.nlm.nih.gov/pubmed/34203861
http://dx.doi.org/10.3390/ijms22126408