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Critical Role of Hemopexin Mediated Cytoprotection in the Pathophysiology of Sickle Cell Disease
Circulating hemopexin is the primary protein responsible for the clearance of heme; therefore, it is a systemic combatant against deleterious inflammation and oxidative stress induced by the presence of free heme. This role of hemopexin is critical in hemolytic pathophysiology. In this review, we ou...
Autores principales: | Ashouri, Rani, Fangman, Madison, Burris, Alicia, Ezenwa, Miriam O., Wilkie, Diana J., Doré, Sylvain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232622/ https://www.ncbi.nlm.nih.gov/pubmed/34203861 http://dx.doi.org/10.3390/ijms22126408 |
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