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Hybrid-Type SELEX for the Selection of Artificial Nucleic Acid Aptamers Exhibiting Cell Internalization Activity

Nucleic acid aptamers have attracted considerable attention as next-generation pharmaceutical agents and delivery vehicles for small molecule drugs and therapeutic oligonucleotides. Chemical modification is an effective approach for improving the functionality of aptamers. However, the process of se...

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Detalles Bibliográficos
Autores principales: Uemachi, Hiro, Kasahara, Yuuya, Tanaka, Keisuke, Okuda, Takumi, Yoneda, Yoshihiro, Obika, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232673/
https://www.ncbi.nlm.nih.gov/pubmed/34204006
http://dx.doi.org/10.3390/pharmaceutics13060888