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Dose-Related Aberrant Inhibition of Intracellular Perforin Expression by S1 Subunit of Spike Glycoprotein That Contains Receptor-Binding Domain from SARS-CoV-2

Studies had shown that severe cases of COVID-19 tend to have high viral loads and correlate with functional impairment of cytotoxic lymphocytes, and the features of cytokine storm syndrome are similar to manifestations of severe influenza that have been partially explained by suppressed perforin exp...

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Detalles Bibliográficos
Autores principales: Huang, Chun-Fu, Hsieh, Szu-Min, Pan, Sung-Ching, Huang, Yu-Shang, Chang, Shan-Chwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232787/
https://www.ncbi.nlm.nih.gov/pubmed/34203929
http://dx.doi.org/10.3390/microorganisms9061303