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Effects of Vitamin B(12) Deficiency on Amyloid-β Toxicity in Caenorhabditis elegans
High homocysteine (Hcy) levels, mainly caused by vitamin B(12) deficiency, have been reported to induce amyloid-β (Aβ) formation and tau hyperphosphorylation in mouse models of Alzheimer’s disease. However, the relationship between B(12) deficiency and Aβ aggregation is poorly understood, as is the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232795/ https://www.ncbi.nlm.nih.gov/pubmed/34203911 http://dx.doi.org/10.3390/antiox10060962 |