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Effects of Vitamin B(12) Deficiency on Amyloid-β Toxicity in Caenorhabditis elegans

High homocysteine (Hcy) levels, mainly caused by vitamin B(12) deficiency, have been reported to induce amyloid-β (Aβ) formation and tau hyperphosphorylation in mouse models of Alzheimer’s disease. However, the relationship between B(12) deficiency and Aβ aggregation is poorly understood, as is the...

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Detalles Bibliográficos
Autores principales: Andra, Arif, Tanigawa, Shoko, Bito, Tomohiro, Ishihara, Atsushi, Watanabe, Fumio, Yabuta, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232795/
https://www.ncbi.nlm.nih.gov/pubmed/34203911
http://dx.doi.org/10.3390/antiox10060962