Lysine methylation shields an intracellular pathogen from ubiquitylation and autophagy

Many intracellular pathogens avoid detection by their host cells. However, it remains unknown how they avoid being tagged by ubiquitin, an initial step leading to antimicrobial autophagy. Here, we show that the intracellular bacterial pathogen Rickettsia parkeri uses two protein-lysine methyltransfe...

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Detalles Bibliográficos
Autores principales: Engström, Patrik, Burke, Thomas P., Tran, Cuong J., Iavarone, Anthony T., Welch, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232902/
https://www.ncbi.nlm.nih.gov/pubmed/34172444
http://dx.doi.org/10.1126/sciadv.abg2517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232902/
https://www.ncbi.nlm.nih.gov/pubmed/34172444
http://dx.doi.org/10.1126/sciadv.abg2517

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