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Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging

The notion that the germ line does not age goes back to the 19th-century ideas of August Weismann. However, being metabolically active, the germ line accumulates damage and other changes over time, i.e., it ages. For new life to begin in the same young state, the germ line must be rejuvenated in the...

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Detalles Bibliográficos
Autores principales: Kerepesi, Csaba, Zhang, Bohan, Lee, Sang-Goo, Trapp, Alexandre, Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232908/
https://www.ncbi.nlm.nih.gov/pubmed/34172448
http://dx.doi.org/10.1126/sciadv.abg6082