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Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging
The notion that the germ line does not age goes back to the 19th-century ideas of August Weismann. However, being metabolically active, the germ line accumulates damage and other changes over time, i.e., it ages. For new life to begin in the same young state, the germ line must be rejuvenated in the...
Autores principales: | Kerepesi, Csaba, Zhang, Bohan, Lee, Sang-Goo, Trapp, Alexandre, Gladyshev, Vadim N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232908/ https://www.ncbi.nlm.nih.gov/pubmed/34172448 http://dx.doi.org/10.1126/sciadv.abg6082 |
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