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Structure of the mycobacterial ESX-5 type VII secretion system pore complex

The ESX-5 type VII secretion system is a membrane-spanning protein complex key to the virulence of mycobacterial pathogens. However, the overall architecture of the fully assembled translocation machinery and the composition of the central secretion pore have remained unknown. Here, we present the h...

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Detalles Bibliográficos
Autores principales: Beckham, Katherine S. H., Ritter, Christina, Chojnowski, Grzegorz, Ziemianowicz, Daniel S., Mullapudi, Edukondalu, Rettel, Mandy, Savitski, Mikhail M., Mortensen, Simon A., Kosinski, Jan, Wilmanns, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232910/
https://www.ncbi.nlm.nih.gov/pubmed/34172453
http://dx.doi.org/10.1126/sciadv.abg9923