Cargando…

Glucagon regulates the stability of REV-ERBα to modulate hepatic glucose production in a model of lung cancer–associated cachexia

Lung adenocarcinoma is associated with cachexia, which manifests as an inflammatory response that causes wasting of adipose tissue and skeletal muscle. We previously reported that lung tumor–bearing (TB) mice exhibit alterations in inflammatory and hormonal signaling that deregulate circadian pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales: Verlande, Amandine, Chun, Sung Kook, Goodson, Maggie O., Fortin, Bridget M., Bae, Hosung, Jang, Cholsoon, Masri, Selma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232919/
https://www.ncbi.nlm.nih.gov/pubmed/34172439
http://dx.doi.org/10.1126/sciadv.abf3885