Cargando…

Glucagon regulates the stability of REV-ERBα to modulate hepatic glucose production in a model of lung cancer–associated cachexia

Lung adenocarcinoma is associated with cachexia, which manifests as an inflammatory response that causes wasting of adipose tissue and skeletal muscle. We previously reported that lung tumor–bearing (TB) mice exhibit alterations in inflammatory and hormonal signaling that deregulate circadian pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verlande, Amandine, Chun, Sung Kook, Goodson, Maggie O., Fortin, Bridget M., Bae, Hosung, Jang, Cholsoon, Masri, Selma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232919/ https://www.ncbi.nlm.nih.gov/pubmed/34172439 http://dx.doi.org/10.1126/sciadv.abf3885

Ejemplares similares

Exogenous detection of (13)C-glucose metabolism in tumor and diet-induced obesity models
por: Verlande, Amandine, et al.
Publicado: (2022)

Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ
por: Cho, Han, et al.
Publicado: (2012)

Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells
por: Vieira, Elaine, et al.
Publicado: (2013)

REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output
por: Ikeda, Ryosuke, et al.
Publicado: (2019)

REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor
por: Okabe, Takashi, et al.
Publicado: (2016)

Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle
por: Amador, Ariadna, et al.
Publicado: (2018)

Direct Regulation of CLOCK Expression by REV-ERB
por: Crumbley, Christine, et al.
Publicado: (2011)

Rev-erbs and Glia—Implications for Neurodegenerative Diseases
por: Griffin, Percy, et al.
Publicado: (2019)

REV-ERB is essential in cardiac fibroblasts homeostasis
por: Luo, Xiaokang, et al.
Publicado: (2022)

The Role of REV-ERB Receptors in Cancer Pathogenesis
por: Gomatou, Georgia, et al.
Publicado: (2023)

Metabolic flux between organs measured by arteriovenous metabolite gradients
por: Bae, Hosung, et al.
Publicado: (2022)

Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation
por: Amador, Ariadna, et al.
Publicado: (2016)

Expression of AFP and Rev-Erb A/Rev-Erb B and N-CoR in fetal rat liver, liver injury and liver regeneration
por: Meier, Volker, et al.
Publicado: (2006)

Regulation of Circadian Behavior and Metabolism by Synthetic REV-ERB Agonists
por: Solt, Laura A., et al.
Publicado: (2012)

Novel Function of Rev-erbα in Promoting Brown Adipogenesis
por: Nam, Deokhwa, et al.
Publicado: (2015)

Rev-erbα in the brain is essential for circadian food entrainment
por: Delezie, Julien, et al.
Publicado: (2016)

Targeting REV-ERBα for therapeutic purposes: promises and challenges
por: Wang, Shuai, et al.
Publicado: (2020)

Downregulation of REV-ERBα is associated with the progression of lung adenocarcinoma
por: Zhang, Hao, et al.
Publicado: (2022)

Circadian clock molecule REV-ERBα regulates lung fibrotic progression through collagen stabilization
por: Wang, Qixin, et al.
Publicado: (2023)

Decreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model
por: Yue, Jiong, et al.
Publicado: (2020)

The Nuclear Receptor Rev-erbα Controls Circadian Thermogenic Plasticity
por: Gerhart-Hines, Zachary, et al.
Publicado: (2013)

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene induced senescence
por: Sulli, Gabriele, et al.
Publicado: (2018)

The Nuclear Receptor and Clock Repressor Rev-erbα Suppresses Myogenesis
por: Chatterjee, Somik, et al.
Publicado: (2019)

REV-ERBα Regulates T(H)17 Cell Development and Autoimmunity
por: Amir, Mohammed, et al.
Publicado: (2018)

Rev-erb in GABAergic Neurons Controls Diurnal Hepatic Insulin Sensitivity
por: Ding, Guolian, et al.
Publicado: (2021)

Myocardial Rev-erb–Mediated Diurnal Metabolic Rhythm and Obesity Paradox
por: Song, Shiyang, et al.
Publicado: (2022)

Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB
por: Murray, Meghan H., et al.
Publicado: (2022)

Role of Circadian Transcription Factor Rev-Erb in Metabolism and Tissue Fibrosis
por: Raza, Ghulam Shere, et al.
Publicado: (2022)

DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα
por: Chini, Claudia C. S., et al.
Publicado: (2013)

Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism
por: Dragan, Morgan, et al.
Publicado: (2023)

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis
por: Le Martelot, Gwendal, et al.
Publicado: (2009)

REV-ERB ALPHA Polymorphism Is Associated with Obesity in the Spanish Obese Male Population
por: Ruano, Elena G., et al.
Publicado: (2014)

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
por: Lam, Michael T.Y., et al.
Publicado: (2013)

In Vitro Metabolic Studies of REV-ERB Agonists SR9009 and SR9011
por: Geldof, Lore, et al.
Publicado: (2016)

Rev-erb Agonist Inhibits Chikungunya and O’nyong’nyong Virus Replication
por: Hwang, Jesse, et al.
Publicado: (2018)

REV-ERB agonism improves liver pathology in a mouse model of NASH
por: Griffett, Kristine, et al.
Publicado: (2020)

Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication
por: Borrmann, Helene, et al.
Publicado: (2020)

Translational Regulation of Clock Genes BMAL1 and REV-ERBα by Polyamines
por: Sakamoto, Akihiko, et al.
Publicado: (2021)

Molecular Dynamics of Cobalt Protoporphyrin Antagonism of the Cancer Suppressor REV-ERBβ
por: Fakih, Taufik Muhammad, et al.
Publicado: (2021)

REV-ERB activation as a novel pharmacological approach for treating inflammatory pain
por: Makhija, Sangeet, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_49363ald67cr6c04s05lohdf0l