HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

Chromatin, which consists of DNA and associated proteins, contains genetic information and is a mechanical component of the nucleus. Heterochromatic histone methylation controls nucleus and chromosome stiffness, but the contribution of heterochromatin protein HP1α (CBX5) is unknown. We used a novel...

Descripción completa

Detalles Bibliográficos
Autores principales: Strom, Amy R, Biggs, Ronald J, Banigan, Edward J, Wang, Xiaotao, Chiu, Katherine, Herman, Cameron, Collado, Jimena, Yue, Feng, Ritland Politz, Joan C, Tait, Leah J, Scalzo, David, Telling, Agnes, Groudine, Mark, Brangwynne, Clifford P, Marko, John F, Stephens, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233041/
https://www.ncbi.nlm.nih.gov/pubmed/34106828
http://dx.doi.org/10.7554/eLife.63972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233041/
https://www.ncbi.nlm.nih.gov/pubmed/34106828
http://dx.doi.org/10.7554/eLife.63972

Ejemplares similares