Evaluation and validation of next-generation sequencing to support lot release for a novel type 2 oral poliovirus vaccine

A novel, genetically-stabilized type 2 oral polio vaccine (nOPV2), developed to assist in the global polio eradication program, was recently the first-ever vaccine granted Emergency Use Listing by the WHO. Lot release tests for this vaccine included—for the first time to our knowledge—the assessment...

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Detalles Bibliográficos
Autores principales: Konz, John O., Schofield, Tim, Carlyle, Sarah, Wahid, Rahnuma, Ansari, Azeem, Strating, Jeroen R.P.M., Yeh, Ming Te, Manukyan, Hasmik, Smits, Saskia L., Tritama, Erman, Rahmah, Latri, Ugiyadi, Dori, Andino, Raul, Laassri, Majid, Chumakov, Konstantin, Macadam, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233139/
https://www.ncbi.nlm.nih.gov/pubmed/34195600
http://dx.doi.org/10.1016/j.jvacx.2021.100102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233139/
https://www.ncbi.nlm.nih.gov/pubmed/34195600
http://dx.doi.org/10.1016/j.jvacx.2021.100102

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