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Evaluation and validation of next-generation sequencing to support lot release for a novel type 2 oral poliovirus vaccine
A novel, genetically-stabilized type 2 oral polio vaccine (nOPV2), developed to assist in the global polio eradication program, was recently the first-ever vaccine granted Emergency Use Listing by the WHO. Lot release tests for this vaccine included—for the first time to our knowledge—the assessment...
Autores principales: | Konz, John O., Schofield, Tim, Carlyle, Sarah, Wahid, Rahnuma, Ansari, Azeem, Strating, Jeroen R.P.M., Yeh, Ming Te, Manukyan, Hasmik, Smits, Saskia L., Tritama, Erman, Rahmah, Latri, Ugiyadi, Dori, Andino, Raul, Laassri, Majid, Chumakov, Konstantin, Macadam, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233139/ https://www.ncbi.nlm.nih.gov/pubmed/34195600 http://dx.doi.org/10.1016/j.jvacx.2021.100102 |
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