Cargando…

SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure

In the last several years, NAD+ supplementation has emerged as an innovative and safe therapeutic strategy for a wide spectrum of disorders, including diabetes and neuropathy. However, critical questions remain as to how NAD+ and its precursors are taken up by cells, as well as the effects of long-l...

Descripción completa

Detalles Bibliográficos
Autores principales: Buonvicino, Daniela, Ranieri, Giuseppe, Pittelli, Maria, Lapucci, Andrea, Bragliola, Stefania, Chiarugi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233143/
https://www.ncbi.nlm.nih.gov/pubmed/34097876
http://dx.doi.org/10.1016/j.jbc.2021.100855