An insulin-independent mechanism for transcriptional regulation of Foxo1 in type 2 diabetic mice

Hepatic gluconeogenesis is the major contributor to the hyperglycemia observed in both patients and animals with type 2 diabetes. The transcription factor FOXO1 plays a dominant role in stimulating hepatic gluconeogenesis. FOXO1 is mainly regulated by insulin under physiological conditions, but live...

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Detalles Bibliográficos
Autores principales: Ge, Wenhao, Zhao, Yang, Yang, Yunxia, Ding, Zhao, Xu, Xi, Weng, Dan, Wang, Shiming, Cheng, Rui, Zhang, Jianfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233149/
https://www.ncbi.nlm.nih.gov/pubmed/34058194
http://dx.doi.org/10.1016/j.jbc.2021.100846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233149/
https://www.ncbi.nlm.nih.gov/pubmed/34058194
http://dx.doi.org/10.1016/j.jbc.2021.100846

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