Activity of trastuzumab emtansine (T-DM1) in 3D cell culture

BACKGROUND: Cell spheroids and aggregates generated from three-dimensional (3D) cell culture methods are similar to in vivo tumors in terms of tissue morphology, biology, and gene expression, unlike cells grown in 2D cell cultures. Breast cancer heterogeneity is one of the main drug resistant mechan...

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Detalles Bibliográficos
Autores principales: Boyer, Jean Zheng, Phillips, Gail D. Lewis, Nitta, Hiro, Garsha, Karl, Admire, Brittany, Kraft, Robert, Dennis, Eslie, Vela, Elizabeth, Towne, Penny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233276/
https://www.ncbi.nlm.nih.gov/pubmed/34091830
http://dx.doi.org/10.1007/s10549-021-06272-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233276/
https://www.ncbi.nlm.nih.gov/pubmed/34091830
http://dx.doi.org/10.1007/s10549-021-06272-x

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