The prognostic significance of Flap Endonuclease 1 (FEN1) in breast ductal carcinoma in situ

BACKGROUND: Impaired DNA repair mechanism is one of the cancer hallmarks. Flap Endonuclease 1 (FEN1) is essential for genomic integrity. FEN1 has key roles during base excision repair (BER) and replication. We hypothesised a role for FEN1 in breast cancer pathogenesis. This study aims to assess the...

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Detalles Bibliográficos
Autores principales: Al-Kawaz, Abdulbaqi, Miligy, Islam M., Toss, Michael S., Mohammed, Omar J., Green, Andrew R., Madhusudan, Srinivasan, Rakha, Emad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233293/
https://www.ncbi.nlm.nih.gov/pubmed/34117958
http://dx.doi.org/10.1007/s10549-021-06271-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233293/
https://www.ncbi.nlm.nih.gov/pubmed/34117958
http://dx.doi.org/10.1007/s10549-021-06271-y

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