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A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs
The systemic therapeutic utilisation of RNA interference (RNAi) is limited by the non-specific off-target effects, which can have severe adverse impacts in clinical applications. The accurate use of RNAi requires tumour-specific on-demand conditional activation to eliminate the off-target effects of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233311/ https://www.ncbi.nlm.nih.gov/pubmed/34172725 http://dx.doi.org/10.1038/s41467-021-24191-9 |