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Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma

Cancer stem cells (CSCs) play a critical role in invasive growth and metastasis of human head and neck squamous cell carcinoma (HNSCC). Although significant progress has been made in understanding the self-renewal and pro-tumorigenic potentials of CSCs, a key challenge remains on how to eliminate CS...

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Detalles Bibliográficos
Autores principales: Dong, Jiaqiang, Li, Jiong, Li, Yang, Ma, Zhikun, Yu, Yongxin, Wang, Cun-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233332/
https://www.ncbi.nlm.nih.gov/pubmed/34172737
http://dx.doi.org/10.1038/s41467-021-24137-1