Cargando…

Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma

Cancer stem cells (CSCs) play a critical role in invasive growth and metastasis of human head and neck squamous cell carcinoma (HNSCC). Although significant progress has been made in understanding the self-renewal and pro-tumorigenic potentials of CSCs, a key challenge remains on how to eliminate CS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Jiaqiang, Li, Jiong, Li, Yang, Ma, Zhikun, Yu, Yongxin, Wang, Cun-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233332/ https://www.ncbi.nlm.nih.gov/pubmed/34172737 http://dx.doi.org/10.1038/s41467-021-24137-1

Ejemplares similares

A Super-Enhancer Driven by FOSL1 Controls miR-21-5p Expression in Head and Neck Squamous Cell Carcinoma
por: Wan, Yuehan, et al.
Publicado: (2021)

A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival
por: Cheng, Yingduan, et al.
Publicado: (2016)

Targeting cancer stem cells in squamous cell carcinoma
por: Chen, Demeng, et al.
Publicado: (2019)

Screening and cellular validation of prognostic genes regulated by super enhancers in oral squamous cell carcinoma
por: Zhang, Liru, et al.
Publicado: (2021)

Super-enhancers in esophageal carcinoma: Transcriptional addictions and therapeutic strategies
por: Shi, Yang, et al.
Publicado: (2022)

Enhancer and super‐enhancer: Positive regulators in gene transcription
por: Peng, Yanling, et al.
Publicado: (2018)

Genome-Wide Super-Enhancer-Based Analysis: Identification of Prognostic Genes in Oral Squamous Cell Carcinoma
por: Saito, Tomoaki, et al.
Publicado: (2022)

Super-enhancers complexes zoom in transcription in cancer
por: Wang, MengTing, et al.
Publicado: (2023)

JUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis
por: Jia, Qunying, et al.
Publicado: (2023)

Super Enhancer Profiles Identify Key Cell Identity Genes During Differentiation From Embryonic Stem Cells to Trophoblast Stem Cells Super Enhencers in Trophoblast Differentiation
por: Jia, Rongpu, et al.
Publicado: (2021)

YY1 Positively Regulates Transcription by Targeting Promoters and Super-Enhancers through the BAF Complex in Embryonic Stem Cells
por: Wang, Jia, et al.
Publicado: (2018)

Identification of genes associated with histologic tumor grade of esophageal squamous cell carcinoma
por: Xing, Jiaqiang, et al.
Publicado: (2017)

KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling
por: Li, Jiong, et al.
Publicado: (2017)

Super-Enhancers in the Regulation of Gene Transcription: General Aspects and Antitumor Targets
por: Bruter, A. V., et al.
Publicado: (2021)

Author Correction: KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling
por: Li, Jiong, et al.
Publicado: (2019)

YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma
por: Xie, Qiang, et al.
Publicado: (2021)

TRAF6 regulates tumour metastasis through EMT and CSC phenotypes in head and neck squamous cell carcinoma
por: Chen, Lei, et al.
Publicado: (2017)

Super-enhancer in prostate cancer: transcriptional disorders and therapeutic targets
por: Chen, Xuanrong, et al.
Publicado: (2020)

Super-enhancers in transcriptional regulation and genome organization
por: Wang, Xi, et al.
Publicado: (2019)

Enhancement and metastasis after immunotherapy of ovine squamous-cell carcinoma.
por: Jun, M. H., et al.
Publicado: (1978)

Control of Embryonic Stem Cell Identity by BRD4-Dependent Transcriptional Elongation of Super-Enhancer-Associated Pluripotency Genes
por: Micco, Raffaella Di, et al.
Publicado: (2014)

Super enhancers targeting ZBTB16 in osteogenesis protect against osteoporosis
por: Yu, Wenhui, et al.
Publicado: (2023)

Identification of super-enhancer-associated transcription factors regulating glucose metabolism in poorly differentiated thyroid carcinoma
por: Liu, Kun, et al.
Publicado: (2022)

Identification of key immune cell-related genes involved in tumorigenesis and prognosis of cervical squamous cell carcinoma
por: Yan, Chunxiao, et al.
Publicado: (2023)

CDK12 orchestrates super‐enhancer‐associated CCDC137 transcription to direct hepatic metastasis in colorectal cancer
por: Dai, Wei, et al.
Publicado: (2022)

Lymph node metastasis in lung squamous cell carcinoma and identification of metastasis‐related genes based on the Cancer Genome Atlas
por: Dong, Ming, et al.
Publicado: (2019)

Growth differentiation factor 6, a repressive target of EZH2, promotes the commitment of human embryonic stem cells to mesenchymal stem cells
por: Deng, Pend, et al.
Publicado: (2020)

Super-enhancer-associated gene CAPG promotes AML progression
por: Ma, Qian, et al.
Publicado: (2023)

Super-enhancers conserved within placental mammals maintain stem cell pluripotency
por: Zhang, Juqing, et al.
Publicado: (2022)

Super-enhancer-associated transcription factors collaboratively regulate trophoblast-active gene expression programs in human trophoblast stem cells
por: Kim, Mijeong, et al.
Publicado: (2023)

The transcriptional regulator Aire binds to and activates super-enhancers
por: Bansal, Kushagra, et al.
Publicado: (2017)

E2F1 combined with LINC01004 super-enhancer to promote hepatocellular carcinoma cell proliferation and metastasis
por: Li, Jingxuan, et al.
Publicado: (2023)

Expression and functional regulation of stemness gene Lgr5 in esophageal squamous cell carcinoma
por: Lv, Zhuan, et al.
Publicado: (2017)

PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions
por: Huang, Xiaona, et al.
Publicado: (2019)

Mining of prognosis-related genes in cervical squamous cell carcinoma immune microenvironment
por: Ma, Jiong, et al.
Publicado: (2020)

Generation of a squamous cell carcinoma mouse model for lineage tracing of BMI1+ cancer stem cells
por: Chen, Demeng, et al.
Publicado: (2021)

Enhanced transcriptional heterogeneity mediated by NF-κB super-enhancers
por: Wibisana, Johannes N., et al.
Publicado: (2022)

Author Correction: Super enhancers targeting ZBTB16 in osteogenesis protect against osteoporosis
por: Yu, Wenhui, et al.
Publicado: (2023)

Choroidal metastasis from esophageal squamous cell carcinoma
por: Chang, Shin-Yu, et al.
Publicado: (2018)

G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma
por: Liu, Shuli, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7v07qa4hubi7ia4468gflsg22p