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Catalytic asymmetric nucleophilic fluorination using BF(3)·Et(2)O as fluorine source and activating reagent
Fluorination using chiral catalytic methods could result in a direct access to asymmetric fluorine chemistry. However, challenges in catalytic asymmetric fluorinations, especially the longstanding stereochemical challenges existed in BF(3)·Et(2)O-based fluorinations, have not yet been addressed. Her...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233348/ https://www.ncbi.nlm.nih.gov/pubmed/34172752 http://dx.doi.org/10.1038/s41467-021-24278-3 |