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Catalytic asymmetric nucleophilic fluorination using BF(3)·Et(2)O as fluorine source and activating reagent

Fluorination using chiral catalytic methods could result in a direct access to asymmetric fluorine chemistry. However, challenges in catalytic asymmetric fluorinations, especially the longstanding stereochemical challenges existed in BF(3)·Et(2)O-based fluorinations, have not yet been addressed. Her...

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Detalles Bibliográficos
Autores principales: Zhu, Weiwei, Zhen, Xiang, Wu, Jingyuan, Cheng, Yaping, An, Junkai, Ma, Xingyu, Liu, Jikun, Qin, Yuji, Zhu, Hao, Xue, Jijun, Jiang, Xianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233348/
https://www.ncbi.nlm.nih.gov/pubmed/34172752
http://dx.doi.org/10.1038/s41467-021-24278-3

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