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p38-MAPK-mediated translation regulation during early blastocyst development is required for primitive endoderm differentiation in mice

Successful specification of the two mouse blastocyst inner cell mass (ICM) lineages (the primitive endoderm (PrE) and epiblast) is a prerequisite for continued development and requires active fibroblast growth factor 4 (FGF4) signaling. Previously, we identified a role for p38 mitogen-activated prot...

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Detalles Bibliográficos
Autores principales: Bora, Pablo, Gahurova, Lenka, Mašek, Tomáš, Hauserova, Andrea, Potěšil, David, Jansova, Denisa, Susor, Andrej, Zdráhal, Zbyněk, Ajduk, Anna, Pospíšek, Martin, Bruce, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233355/
https://www.ncbi.nlm.nih.gov/pubmed/34172827
http://dx.doi.org/10.1038/s42003-021-02290-z