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p38-MAPK-mediated translation regulation during early blastocyst development is required for primitive endoderm differentiation in mice
Successful specification of the two mouse blastocyst inner cell mass (ICM) lineages (the primitive endoderm (PrE) and epiblast) is a prerequisite for continued development and requires active fibroblast growth factor 4 (FGF4) signaling. Previously, we identified a role for p38 mitogen-activated prot...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233355/ https://www.ncbi.nlm.nih.gov/pubmed/34172827 http://dx.doi.org/10.1038/s42003-021-02290-z |