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A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression

CRISPR-based gene drives offer promising means to reduce the burden of pests and vector-borne diseases. These techniques consist of releasing genetically modified organisms carrying CRISPR-Cas nucleases designed to bias their inheritance and rapidly propagate desired modifications. Gene drives can b...

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Detalles Bibliográficos
Autores principales: Taxiarchi, Chrysanthi, Beaghton, Andrea, Don, Nayomi Illansinhage, Kyrou, Kyros, Gribble, Matthew, Shittu, Dammy, Collins, Scott P., Beisel, Chase L., Galizi, Roberto, Crisanti, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233359/
https://www.ncbi.nlm.nih.gov/pubmed/34172748
http://dx.doi.org/10.1038/s41467-021-24214-5