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A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
CRISPR-based gene drives offer promising means to reduce the burden of pests and vector-borne diseases. These techniques consist of releasing genetically modified organisms carrying CRISPR-Cas nucleases designed to bias their inheritance and rapidly propagate desired modifications. Gene drives can b...
Autores principales: | Taxiarchi, Chrysanthi, Beaghton, Andrea, Don, Nayomi Illansinhage, Kyrou, Kyros, Gribble, Matthew, Shittu, Dammy, Collins, Scott P., Beisel, Chase L., Galizi, Roberto, Crisanti, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233359/ https://www.ncbi.nlm.nih.gov/pubmed/34172748 http://dx.doi.org/10.1038/s41467-021-24214-5 |
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