Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase

Despite the well-established chemical processes for C-D bond formation, the toolbox of enzymatic methodologies for deuterium incorporation has remained underdeveloped. Here we describe a photodecarboxylase from Chlorella variabilis NC64A (CvFAP)-catalyzed approach for the decarboxylative deuteration...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Fan, Jiajie, Lou, Yujiao, Xu, Weihua, Wang, Zhiguo, Li, Danyang, Zhou, Haonan, Lin, Xianfu, Wu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233396/
https://www.ncbi.nlm.nih.gov/pubmed/34172745
http://dx.doi.org/10.1038/s41467-021-24259-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233396/
https://www.ncbi.nlm.nih.gov/pubmed/34172745
http://dx.doi.org/10.1038/s41467-021-24259-6

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