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Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase

Despite the well-established chemical processes for C-D bond formation, the toolbox of enzymatic methodologies for deuterium incorporation has remained underdeveloped. Here we describe a photodecarboxylase from Chlorella variabilis NC64A (CvFAP)-catalyzed approach for the decarboxylative deuteration...

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Detalles Bibliográficos
Autores principales:	Xu, Jian, Fan, Jiajie, Lou, Yujiao, Xu, Weihua, Wang, Zhiguo, Li, Danyang, Zhou, Haonan, Lin, Xianfu, Wu, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233396/ https://www.ncbi.nlm.nih.gov/pubmed/34172745 http://dx.doi.org/10.1038/s41467-021-24259-6

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