Kras activation in endometrial organoids drives cellular transformation and epithelial-mesenchymal transition

KRAS, an oncogene, is frequently activated by mutations in many cancers. Kras-driven adenocarcinoma development in the lung, pancreas, and biliary tract has been extensively studied using gene targeting in mice. By taking the organoid- and allograft-based genetic approach to these organs, essentiall...

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Detalles Bibliográficos
Autores principales: Maru, Yoshiaki, Tanaka, Naotake, Tatsumi, Yasutoshi, Nakamura, Yuki, Itami, Makiko, Hippo, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233399/
https://www.ncbi.nlm.nih.gov/pubmed/34172714
http://dx.doi.org/10.1038/s41389-021-00337-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233399/
https://www.ncbi.nlm.nih.gov/pubmed/34172714
http://dx.doi.org/10.1038/s41389-021-00337-8

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