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Kras activation in endometrial organoids drives cellular transformation and epithelial-mesenchymal transition
KRAS, an oncogene, is frequently activated by mutations in many cancers. Kras-driven adenocarcinoma development in the lung, pancreas, and biliary tract has been extensively studied using gene targeting in mice. By taking the organoid- and allograft-based genetic approach to these organs, essentiall...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233399/ https://www.ncbi.nlm.nih.gov/pubmed/34172714 http://dx.doi.org/10.1038/s41389-021-00337-8 |