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In-depth correlation analysis demonstrates that 4-hydroxyproline at the Yaa position of Gly-Xaa-Yaa repeats dominantly stabilizes collagen triple helix
There is a general consensus that collagen stability is largely maintained by Pro and its major hydroxylated form, 4-hydroxyproline (4Hyp). However, positional difference in their stabilizing effect at the Xaa or Yaa position of collagenous Gly-Xaa-Yaa sequences has remained inconclusive. Here, we p...
Autores principales: | Taga, Yuki, Tanaka, Keisuke, Hattori, Shunji, Mizuno, Kazunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233474/ https://www.ncbi.nlm.nih.gov/pubmed/34195597 http://dx.doi.org/10.1016/j.mbplus.2021.100067 |
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