Influence of SLCO1B1 521T>C, UGT2B7 802C>T and IMPDH1 −106G>A Genetic Polymorphisms on Mycophenolic Acid Levels and Adverse Reactions in Chinese Autoimmune Disease Patients

INTRODUCTION: Mycophenolate mofetil (MMF), a new type of immunosuppressant, has emerged as a frontline agent for treating autoimmune diseases. Mycophenolic acid (MPA) is an active metabolite of MMF. MPA exposure varies greatly among individuals, which may lead to adverse drug reactions such as gastr...

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Detalles Bibliográficos
Autores principales: Shu, Qing, Fan, Qingqing, Hua, Bingzhu, Liu, Hang, Wang, Shiying, Liu, Yunxing, Yao, Yao, Xie, Han, Ge, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233479/
https://www.ncbi.nlm.nih.gov/pubmed/34188518
http://dx.doi.org/10.2147/PGPM.S295964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233479/
https://www.ncbi.nlm.nih.gov/pubmed/34188518
http://dx.doi.org/10.2147/PGPM.S295964

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