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Experimental Resurrection of Ancestral Mammalian CPEB3 Ribozymes Reveals Deep Functional Conservation

Self-cleaving ribozymes are genetic elements found in all domains of life, but their evolution remains poorly understood. A ribozyme located in the second intron of the cytoplasmic polyadenylation binding protein 3 gene (CPEB3) shows high sequence conservation in mammals, but little is known about t...

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Detalles Bibliográficos
Autores principales: Bendixsen, Devin P., Pollock, Tanner B., Peri, Gianluca, Hayden, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233481/
https://www.ncbi.nlm.nih.gov/pubmed/33720319
http://dx.doi.org/10.1093/molbev/msab074