Meropenem-Vaborbactam as Salvage Therapy for Ceftazidime-Avibactam-, Cefiderocol-Resistant ST-512 Klebsiella pneumoniae–Producing KPC-31, a D179Y Variant of KPC-3

A 68-year-old man had recurrent bacteremia by Klebsiella pneumoniae carbapenemase (KPC)–producing K. pneumoniae resistant to ceftazidime-avibactam and cefiderocol. The sequencing of a target region showed that it harbored a KPC-3 variant enzyme (D179Y; KPC-31), which confers resistance to ceftazidim...

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Detalles Bibliográficos
Autores principales: Tiseo, Giusy, Falcone, Marco, Leonildi, Alessandro, Giordano, Cesira, Barnini, Simona, Arcari, Gabriele, Carattoli, Alessandra, Menichetti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
ID Teaching Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233566/
https://www.ncbi.nlm.nih.gov/pubmed/34189161
http://dx.doi.org/10.1093/ofid/ofab141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233566/
https://www.ncbi.nlm.nih.gov/pubmed/34189161
http://dx.doi.org/10.1093/ofid/ofab141

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