Cargando…
Astrocytic apoE4 and tau: Deadly combination for neurons
New data from Wang and colleagues(1) suggest that astrocyte-derived apoE4 drives tau-mediated neurodegeneration. This research highlights how a genetic risk factor for Alzheimer’s disease is a major determinant of neurodegeneration in tau-expressing neurons by regulating non-cell-autonomous pathways...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233647/ https://www.ncbi.nlm.nih.gov/pubmed/34195681 http://dx.doi.org/10.1016/j.xcrm.2021.100316 |