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Fluconazole nanoparticles prepared by antisolvent precipitation technique: Physicochemical, in vitro, ex vivo and in vivo ocular evaluation

The goal of this research was to prepare and characterize nanonized particles of the antifungal drug, fluconazole (FLZ) using antisolvent precipitation nanonization technique to improve its ocular permeation. The impact of various concentrations of different stabilizers, namely Pluronic F-127 (PL F...

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Detalles Bibliográficos
Autores principales: El Sayeh F. Abou El Ela, Amal, Abbas Ibrahim, Mohamed, Alqahtani, Yara, Almomen, Aliyah, Sfouq Aleanizy, Fadilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233650/
https://www.ncbi.nlm.nih.gov/pubmed/34194264
http://dx.doi.org/10.1016/j.jsps.2021.04.018