Over-expression of the constitutive AMPylase FIC-1(E274G) does not deplete cellular ATP pools in C. elegans

Protein AMPylation has emerged as a posttranslational protein modification regulating cellular proteostasis. AMPylation is conferred by Fic AMPylases, which catalyze the covalent attachment of AMP to target proteins at the expense of ATP. Over-expression of constitutive-active Fic AMPylases is toxic...

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Detalles Bibliográficos
Autores principales: Champion, Margaret, Truttmann, Matthias C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233689/
https://www.ncbi.nlm.nih.gov/pubmed/34189425
http://dx.doi.org/10.17912/micropub.biology.000409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233689/
https://www.ncbi.nlm.nih.gov/pubmed/34189425
http://dx.doi.org/10.17912/micropub.biology.000409

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