Administration of AAV-Alpha Synuclein NAC Antibody Improves Locomotor Behavior in Rats Overexpressing Alpha Synuclein

Accumulation of α-Synuclein (αSyn) in nigral dopaminergic neurons is commonly seen in patients with Parkinson′s disease (PD). We recently reported that transduction of intracellular single-chain intrabody targeting the 53–87 amino acid residues of human αSyn by recombinant adeno associated viral vec...

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Detalles Bibliográficos
Autores principales: Chen, Yun-Hsiang, Wu, Kuo-Jen, Hsieh, Wei, Harvey, Brandon K., Hoffer, Barry J., Wang, Yun, Yu, Seong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233769/
https://www.ncbi.nlm.nih.gov/pubmed/34205689
http://dx.doi.org/10.3390/genes12060948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233769/
https://www.ncbi.nlm.nih.gov/pubmed/34205689
http://dx.doi.org/10.3390/genes12060948

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