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Administration of AAV-Alpha Synuclein NAC Antibody Improves Locomotor Behavior in Rats Overexpressing Alpha Synuclein
Accumulation of α-Synuclein (αSyn) in nigral dopaminergic neurons is commonly seen in patients with Parkinson′s disease (PD). We recently reported that transduction of intracellular single-chain intrabody targeting the 53–87 amino acid residues of human αSyn by recombinant adeno associated viral vec...
Autores principales: | Chen, Yun-Hsiang, Wu, Kuo-Jen, Hsieh, Wei, Harvey, Brandon K., Hoffer, Barry J., Wang, Yun, Yu, Seong-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233769/ https://www.ncbi.nlm.nih.gov/pubmed/34205689 http://dx.doi.org/10.3390/genes12060948 |
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