Influence of the FCGR2A rs1801274 and FCGR3A rs396991 Polymorphisms on Response to Abatacept in Patients with Rheumatoid Arthritis

Abatacept (ABA) is an immunosuppressant indicated for treatment of rheumatoid arthritis (RA). Effectiveness might be influenced by clinical RA variants and single-nucleotide polymorphisms (SNPs) in genes encoding protein FCGR2A (His131Arg) and FCGR3A (Phe158Val) involved in pharmacokinetics of ABA....

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Detalles Bibliográficos
Autores principales: Márquez Pete, Noelia, Maldonado Montoro, María del Mar, Pérez Ramírez, Cristina, Martínez Martínez, Fernando, Martínez de la Plata, Juan Enrique, Daddaoua, Abdelali, Jiménez Morales, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233911/
https://www.ncbi.nlm.nih.gov/pubmed/34207385
http://dx.doi.org/10.3390/jpm11060573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233911/
https://www.ncbi.nlm.nih.gov/pubmed/34207385
http://dx.doi.org/10.3390/jpm11060573

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