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Upper Aerodigestive Tract Squamous Cell Carcinomas Show Distinct Overall DNA Methylation Profiles and Different Molecular Mechanisms behind WNT Signaling Disruption

SIMPLE SUMMARY: Squamous cell carcinomas of the upper aerodigestive tract are highly incident, lethal, and share the same epithelial lining of origin, risk factors and genetic alterations. However, their biological and clinical behaviors differ, having an impact on patient survival. This study aimed...

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Detalles Bibliográficos
Autores principales: Soares-Lima, Sheila Coelho, Mehanna, Hisham, Camuzi, Diego, de Souza-Santos, Paulo Thiago, Simão, Tatiana de Almeida, Nicolau-Neto, Pedro, Almeida Lopes, Monique de Souza, Cuenin, Cyrille, Talukdar, Fazlur Rahman, Batis, Nikolaos, Costa, Izabella, Dias, Fernando, Degli Esposti, Davide, Boroni, Mariana, Herceg, Zdenko, Ribeiro Pinto, Luis Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234055/
https://www.ncbi.nlm.nih.gov/pubmed/34208581
http://dx.doi.org/10.3390/cancers13123014