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Upper Aerodigestive Tract Squamous Cell Carcinomas Show Distinct Overall DNA Methylation Profiles and Different Molecular Mechanisms behind WNT Signaling Disruption
SIMPLE SUMMARY: Squamous cell carcinomas of the upper aerodigestive tract are highly incident, lethal, and share the same epithelial lining of origin, risk factors and genetic alterations. However, their biological and clinical behaviors differ, having an impact on patient survival. This study aimed...
Autores principales: | Soares-Lima, Sheila Coelho, Mehanna, Hisham, Camuzi, Diego, de Souza-Santos, Paulo Thiago, Simão, Tatiana de Almeida, Nicolau-Neto, Pedro, Almeida Lopes, Monique de Souza, Cuenin, Cyrille, Talukdar, Fazlur Rahman, Batis, Nikolaos, Costa, Izabella, Dias, Fernando, Degli Esposti, Davide, Boroni, Mariana, Herceg, Zdenko, Ribeiro Pinto, Luis Felipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234055/ https://www.ncbi.nlm.nih.gov/pubmed/34208581 http://dx.doi.org/10.3390/cancers13123014 |
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